https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Outcome predictors of immune-mediated necrotizing myopathy—a retrospective, multicentre study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50517 Tue 08 Aug 2023 14:23:37 AEST ]]> Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13924 −11, odds ratio (OR) = 1.32), with the A allele (coding for histadine) conferring elevated disease risk. The second locus is at 19q13, (P = 2.51 x 10−9, OR = 1.42 for the rs2233152 SNP near MIA and RAB4B; P = 1.68 x 10−12, OR = 1.52 for rs28493229 in ITPKC), which confirms previous findings1. The involvement of the FCGR2A locus may have implications for understanding immune activation in Kawasaki disease pathogenesis and the mechanism of response to intravenous immunoglobulin, the only proven therapy for this disease.]]> Sat 24 Mar 2018 08:24:48 AEDT ]]>